Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 4
Harvey R. Herschman, Weilin Xie, Srinivasta Reddy (auth.), Kenneth V. Honn, Lawrence J. Marnett, Santosh Nigam, Edward A. Dennis (eds.)
Since their discovery over sixty years ago, eicosanoids have come to represent a diverse family of bioactive lipid modulators, including prostaglandins, thromboxanes, leukotrienes, lipoxins, isoprostanes, hepoxilins, hydroxy acids, epoxy and hydroxy fatty acids. This book contains conference presentations regarding the regulation of eicosanoid enzymes and, in particular, cyclooxygenases, lipoxygenases, and phospholipases. In addition, recent evidence over the last seven years has led to the identification of a number of receptors for these bioactive lipids. The new field of isoprostanes is also represented. It has become increasingly evident that eicosanoids play a critical role in signal transduction, both in normal cells and in pathological processes. These aspects are discussed in relation to cellular events, such as apoptosis, angiogenesis, and cancer prevention and treatment.
Категорії:
Рік:
1999
Видання:
1
Видавництво:
Springer US
Мова:
english
Сторінки:
699
ISBN 10:
1461547938
ISBN 13:
9781461547938
Серії:
Advances in Experimental Medicine and Biology 469
Файл:
PDF, 26.13 MB
IPFS:
,
english, 1999
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