Metabolite safety in drug development

Main
Metabolite safety in drug development

Metabolite safety in drug development

Name: Metabolite safety in drug development
ISBN: 9781118949689

Iverson, Suzanne L., Smith, Dennis A

0 / 0

0 comments

Наскільки Вам сподобалась ця книга?

Яка якість завантаженого файлу?

Скачайте книгу, щоб оцінити її якість

Яка якість скачаних файлів?

"A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental designs critical for metabolite studies. It features case studies of lessons learned and real world examples, along with regulatory perspectives from the US FDA and EMA. •€€ €Reviews the analytical techniques and experimental designs critical for metabolite studies •€€ €Covers methods including chirality, species differences, mass spectrometry, radiolabels, and in vitro / in vivo correlation •€€ €Discusses target pharmacology, in vitro systems aligned to toxicity tests, and drug-drug interactions •€€ €Includes perspectives from authors with firsthand involvement in industry and the study of drug metabolites, including viewpoints that have influenced regulatory guidelines"--

"This book focuses on the characterization of metabolites once a drug candidate is selected, featuring case studies to illustrate lessons learned and a perspective on future directions"--
Abstract: A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental designs critical for metabolite studies. It features case studies of lessons learned and real world examples, along with regulatory perspectives from the US FDA and EMA.

Рік:

2016

Видавництво:

John Wiley & Sons Inc

Мова:

english

Сторінки:

350

ISBN 10:

1118949684

ISBN 13:

9781118949689