Clusterin in Normal Brain Functions and During Neurodegeneration
Caleb Ellicott Finch
Clusterin is a multifunctional protein which was independently discovered by more than ten different research groups in the 1980s. New roles of clusterin in brain functions have come to llight which are summarized here by the researchers involved. Recent discoveries include a unique lipoprotein particle containing clusterin and apoE secreted by astrocytes, and the ability of clusterin to promote neurotoxic activities of the amyloid beta peptide, but also to be neuroprotective. Also included is recent information about clusterin and Alzheimer's disease. In all, this is a comprehensive and up-to-date review of clusterin in the brain.
Категорії:
Рік:
1999
Видання:
1st
Видавництво:
Landes Bioscience
Мова:
english
Сторінки:
133
ISBN 10:
1570595836
ISBN 13:
9781570595837
Серії:
Neuroscience Intelligence Unit
Файл:
PDF, 2.30 MB
IPFS:
,
english, 1999